• When compared with lidocaine both amiodarone and nifekalant

  2019-04-26

  

  When compared with lidocaine, both amiodarone and nifekalant were proved similarly effective for ventricular arrhythmias suppression. These drugs, however, have characteristic adverse effects, such as negative inotropic and chronotropic outcomes (amiodarone), and QT prolongation resulting in torsade

• It is noted that in this study

  2019-04-26

  

  It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation

• br Conflict of interest br Introduction A

  2019-04-26

  

  Conflict of interest Introduction A large number of recent reports suggest that early repolarization (ER) and J waves are associated with the occurrence of ventricular fibrillation (VF) [1–4]. In particular, the presence of J waves in global leads, including the inferolateral leads, is thought

• br Study limitations br Introduction The spread of basic

  2019-04-26

  

  Study limitations Introduction The spread of basic life support (BLS), including use of automated external defibrillators in the general public, may increase the chance of survival from sudden cardiac death (SCD). Survivors usually have underlying cardiac diseases, such as coronary artery dise

• RANK RANKL The RANK RANKL signaling pathway is a critical

  2019-04-26

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• Despite our best efforts the

  2019-04-26

  

  Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po

• br To see how the quantity of osteosarcoma

  2019-04-25

  

  To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma stat 3 inhibitor in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary data

• Vaccines for rotavirus and cholera the two

  2019-04-25

  

  Vaccines for rotavirus and cholera—the two diseases with the highest child mortality rates and a significant fraction of the global diarrhoeal burden—are at preliminary stages of implementation. The use of vaccination as a global primary-prevention strategy can also be rapidly strengthened with the

• Buturovic and Ignatovic rightly point out that present day f

  2019-04-25

  

  Buturovic and Ignatovic rightly point out that present-day formula is different from the type of milk received by Brazilian infants born in the early 1980s, particularly because long-chain polyunsaturated fatty acids have been added to modern products. Nevertheless, modern biology is constantly unco

• C sar y Rosa Mar a posan por la insistencia

  2019-04-25

  

  César y Rosa María posan por la insistencia de Menéndez. Montes tiene muy claro ese momento, “yo estaba recargado en mi mano y entonces Mario vio eso y le dice rsv Rodrigo, ‘¡Rodrigo ven, ven!’, y el otro viene corriendo, yo volteo y Mario me dice: ‘ponte así como estabas, no te muevas, pero pon la

• En el segundo caso la Espa a

  2019-04-25

  

  En el segundo caso, la España republicana se constituye como un espejo quebrado, aquello destruido, perdido y que es mejor olvidar para atender la historia urgente y presente del territorio latinoamericano, de muestra vale el ejemplo citado que refiere EZ Cap Reagent GG (3\' OMe) la importancia de c

• phorbol Funding NIH K AI PATH Gates

  2019-04-25

  

  Funding NIH K23-AI103105, PATH, Gates Foundation 50274, UW MSRTP, AOA Carolyn Kuckein Fellowship, IDSA Medical Scholars. Declaration of interests Abstract Background Safe, timely and accessible global essential surgery and anaesthesia, once neglected in global health, is now an integral part of

• The primary outcome was local recurrence or metastasis

  2019-04-25

  

  The primary outcome was local recurrence or metastasis. The secondary outcome included functional outcome based on Musculoskeletal Tumor Society (MSTS) score. Data for the study were retrieved from hospital records, maintained oncological files, surgical files, and clinical examination at the most r

• In patients with surgically corrected CHD the anatomic posit

  2019-04-25

  

  In patients with surgically corrected CHD, the anatomic position of the atriotomy scar as the arrhythmogenic substrate is commonly found in the free wall and not in the septum [8]. The cause of this large area of low voltage (“atrial myopathy”) is unclear. Possible explanations include interruption

• We have recently completed a prospective randomized feasibil

  2019-04-25

  

  We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co

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